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1

ChemInform Abstract: Thiazolo[4,5-d]pyrimidine Thiones and -ones as Corticotropin-Releasing Hormone (CRH-R1) Receptor Antagonists.

James P. Beck, Matt A. Curry, Robert J. Chorvat, Larry W. Fitzgerald, Paul J. Gilligan, Robert Zaczek, George L. Trainor

Journal:

Year:

1999

File:

PDF, 33 KB

1999

2

Synthesis and unexpected reactions of 2-Hydroxy-3-pyridinylacetic hydrazides. Formation of 2H-Pyrrolo[2,3-b]pyridin-2-ones

Christopher A. Teleha, Roger A. Greenberg, Robert J. Chorvat

Journal:

Journal of Heterocyclic Chemistry

Year:

1998

File:

PDF, 391 KB

1998

3

New cardiovascular drugs 1986. Edited by Alexander Scriabine. Raven Press: New York. 1986. xi + 274 pp. 16 × 24 cm. ISBN 0-88167-209-2. $65.00

Robert J. Chorvat

Journal:

Journal of Pharmaceutical Sciences

Year:

1987

Language:

english

File:

PDF, 141 KB

english, 1987

4

The synthesis of annelated 3-cyano-2-pyridones

Robert J. Chorvat, Suzanne Evans Radak

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 203 KB

english, 1980

5

The total synthesis of (±)-2-azaestradiol-3-methyl ether

Robert J. Chorvat, Raphael Pappo

Journal:

Tetrahedron Letters

Year:

1975

Language:

english

File:

PDF, 230 KB

english, 1975

6

Rates of exchange of substituted phosphonium salts

Sheldon E. Cremer, Robert J. Chorvat

Journal:

Tetrahedron Letters

Year:

1966

Language:

english

File:

PDF, 135 KB

english, 1966

7

Pyramidal inversion in substituted phosphetanes

Sheldon E. Cremer, Robert J. Chorvat, C.H. Chang, Donald W. Davis

Journal:

Tetrahedron Letters

Year:

1968

Language:

english

File:

PDF, 178 KB

english, 1968

8

The synthesis of 2-azasteroids

Raphael Pappo, Robert J. Chorvat

Journal:

Tetrahedron Letters

Year:

1972

Language:

english

File:

PDF, 243 KB

english, 1972

9

Rearrangement reactions in four-membered ring phosphorus heterocycles

Sheldon E. Cremer, Robert J. Chorvat

Journal:

Tetrahedron Letters

Year:

1968

Language:

english

File:

PDF, 233 KB

english, 1968

10

Thiazolo[4,5-d]pyrimidine thiones and -ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

James P. Beck, Matt A. Curry, Robert J. Chorvat, Larry W. Fitzgerald, Paul J. Gilligan, Robert Zaczek, George L. Trainor

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 219 KB

english, 1999

11

Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors

Argyrios G. Arvanitis, Everett L. Scholfield, Dimitri Grigoriadis, Peter G. Heytler, Jack Bowdle, Robert J. Chorvat

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 233 KB

english, 1996

12

Linopirdine: Pharmacology of a Neurotransmitter Release Enhancer

Robert Zaczek, Robert J. Chorvat, Barry S. Brown

Journal:

CNS Drug Reviews

Year:

1997

Language:

english

File:

PDF, 890 KB

english, 1997

13

Synthesis of 3,9-dihydro-3,9-dioxo-2H-indeno[2,1-c] pyridine-4-carbonitriles

Robert J. Chorvat, Bipin N. Desai

Journal:

Journal of Heterocyclic Chemistry

Year:

1980

File:

PDF, 236 KB

1980

14

Light-mimicking cockroaches indicate Tertiary origin of recent terrestrial luminescence

Vršanský, Peter, Chorvát, Dušan, Fritzsche, Ingo, Hain, Miroslav, Ševčík, Robert

Journal:

Naturwissenschaften (The Science of Nature)

Year:

2012

Language:

english

File:

PDF, 889 KB

english, 2012

15

Synthesis, Corticotropin-Releasing Factor Receptor Binding Affinity, and Pharmacokinetic Properties of Triazolo-, Imidazo-, and Pyrrolopyrimidines and -pyridines

Chorvat, Robert J., Bakthavatchalam, Rajagopal, Beck, James P., Gilligan, Paul J., Wilde, Richard G., Cocuzza, Anthony J., Hobbs, Frank W., Cheeseman, Robert S., Curry, Matthew, Rescinito, Joseph P.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 194 KB

english, 1999

16

Non-Peptide Corticotropin-Releasing Hormone Antagonists: Syntheses and Structure−Activity Relationships of 2-Anilinopyrimidines and -triazines

Arvanitis, Argyrios G., Gilligan, Paul J., Chorvat, Robert J., Cheeseman, Robert S., Christos, Thomas E., Bakthavatchalam, Rajagopal, Beck, James P., Cocuzza, Anthony J., Hobbs, Frank W., Wilde, Richa

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

17

22-Hydroxycholesterol derivatives as HMG CoA reductase suppressors and serum cholesterol lowering agents

Chorvat, Robert J., Desai, Bipin N., Radak, Suzanne Evans, Perko, Kathleen T., Miller, James E., Jett, Charlene, Rohrbacher, Elaine

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 1003 KB

english, 1985

18

Peripherally restricted CB1 receptor blockers

Chorvat, Robert J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

19

Synthesis of 4-aryl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyrazines

Chorvat, Robert J., Rorig, Kurt J.

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 430 KB

english, 1988

20

Total synthesis of 2-azaestratrienes

Chorvat, Robert J., Palmer, John R., Pappo, Raphael

Journal:

Journal of Organic Chemistry

Year:

1978

Language:

english

File:

PDF, 1.01 MB

english, 1978

21

JD-5006 and JD-5037: Peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities

Chorvat, Robert J., Berbaum, Jennifer, Seriacki, Kristine, McElroy, John F.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 873 KB

english, 2012

22

Inhibition of Cholesteryl Ester Formation in Human Fibroblasts by an Analogue of 7-ketocholesterol and by Progesterone

Joseph L. Goldstein, Jerry R. Faust, John H. Dygos, Robert J. Chorvat and Michael S. Brown

Journal:

Proceedings of the National Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 867 KB

english, 1978

23

A facile synthesis of (3-methoxyisoquinol-7-yl)acetic acids

Chorvat, Robert J.

Journal:

Journal of Organic Chemistry

Year:

1978

Language:

english

File:

PDF, 462 KB

english, 1978

24

Synthesis of 4-phenyl-5H-pyrido[3,4-b][1,4]benzothiazin-3(2H)-ones (4-phenylazaphenothiazines) via activated dimethylformamide reagents

Chorvat, Robert J., Radak, Suzanne Evans, Desai, Bipin N.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 614 KB

english, 1987

25

Syntheses of substituted phosphetanes and related derivatives

Cremer, Sheldon E., Chorvat, Robert J.

Journal:

Journal of Organic Chemistry

Year:

1967

Language:

english

File:

PDF, 797 KB

english, 1967

26

Synthesis, benzodiazepine receptor binding, and anticonvulsant activity of 2,3-dihydro-3-oxo-5H-pyrido[3,4-b][1,4]benzothiazine-4-carbonitriles

Chorvat, Robert J., Desai, Bipin N., Radak, Suzanne Evans, Bloss, James, Hirsch, James, Tenen, Stanley

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 868 KB

english, 1983

27

Synthesis and structure-activity relationships of a new series of antiarrhythmic agents: 4,4-disubstituted hexahydro-3H-pyrido[1,2-c]pyrimidin-3-ones and related compounds

Chorvat, Robert J., Prodan, Kathleen A., Adelstein, Gilbert W., Rydzewski, Robert M., McLaughlin, Kathleen T., Stamm, Margarete H., Frederick, Leo G., Schniepp, Henry C., Stickney, Janice L.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 995 KB

english, 1985

28

2-Fluoro-4-pyridinylmethyl Analogues of Linopirdine as Orally Active Acetylcholine Release-Enhancing Agents with Good Efficacy and Duration of Action

Earl, Richard A., Zaczek, Robert, Teleha, Christopher A., Fisher, Barbara N., Maciag, Carla M., Marynowski, Maria E., Logue, Andrew R., Tam, S. William, Tinker, William J., Huang, Shiew-Mei, Chorvat,

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 232 KB

english, 1998

29

Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. 2

Chorvat, Robert J., Black, Lawrence A., Ranade, Vasant V., Barcelon-Yang, Cynthia, Stout, David M., Brown, Barry S., Stampfli, Herman F., Quon, Check Y.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 558 KB

english, 1993

30

Corticotropin-Releasing Hormone Receptor Antagonists: Framework Design and Synthesis Guided by Ligand Conformational Studies

Hodge, C. Nicholas, Aldrich, Paul E., Wasserman, Zelda R., Fernandez, Christina H., Nemeth, Gregory A., Arvanitis, Argyrios, Cheeseman, Robert S., Chorvat, Robert J., Ciganek, Engelbert, Christos, Tho

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 274 KB

english, 1999

31

Facile synthesis of 3.beta.-hydroxy-5.alpha.-cholest-8(14)-en-15-one 3-acetate

Chorvat, Robert J., Desai, Bipin N.

Journal:

Journal of Organic Chemistry

Year:

1979

Language:

english

File:

PDF, 459 KB

english, 1979

32

Synthesis of 2-azaestratrienes

Chorvat, Robert J., Pappo, Raphael.

Journal:

Journal of Organic Chemistry

Year:

1976

Language:

english

File:

PDF, 1.05 MB

english, 1976

33

Synthesis and structure-activity relationships of a new series of antiarrhythmic agents: monobasic derivatives of disobutamide

Desai, Bipin N., Fowler, Kerry W., Chorvat, Robert J., Frederick, Leo G., Hatley, Frida R., Rorig, Kurt J., Garthwaite, Susan M.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 945 KB

english, 1988

34

Ion channel modulators that enhance acetylcholine release: potential therapies for Alzheimer’s disease

Chorvat, Robert J, Zaczek, Robert, Brown, Barry S

Journal:

Expert Opinion on Investigational Drugs

Year:

1998

Language:

english

File:

PDF, 226 KB

english, 1998

35

ChemInform Abstract: Peripherally Restricted CB1 Receptor Blockers

Chorvat, Robert J.

Journal:

Year:

2013

File:

PDF, 18 KB

2013

36

Synthesis of S -2- ( ( S )-3-(4-chlorophenyl)- N '-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1 H -pyrazole-1-carboximidamido)-3-(methyl- d 3 )butanamide-d 5 , octa-deuterated JD5037

Iyer, Malliga R., Cinar, Resat, Coffey, Nathan J., Chorvat, Robert J., Kunos, George

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2017

Language:

english

File:

PDF, 980 KB

english, 2017